Search on: DNA POL III 
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Descriptor English:   DNA Polymerase III 
Descriptor Spanish:   ADN Polimerasa III 
Descriptor Portuguese:   DNA Polimerase III 
Synonyms English:   DNA Pol III
DNA Dependent DNA Polymerase III
Polymerase III, DNA
Polymerase delta, DNA
DNA-Dependent DNA Polymerase III
DNA Polymerase delta  
Tree Number:   D08.811.913.696.445.308.300.235
Definition English:   A DNA-dependent DNA polymerase characterized in E. coli and other lower organisms but may be present in higher organisms. Used also for a more complex form of DNA polymerase III designated as DNA polymerase III* or pol III* which is 15 times more active biologically than DNA polymerase I in the synthesis of DNA. This polymerase has both 3'-5' and 5'-3' exonuclease activities, is inhibited by sulfhydryl reagents, and has the same template-primer dependence as pol II. EC 2.7.7.7. 
History Note English:   91(77); for DNA POLYMERASE DELTA use DNA POLYMERASE III (NM) 1980-97 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
CT contraindications DF deficiency
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
SE secretion ST standards
SD supply & distribution TU therapeutic use
TO toxicity UL ultrastructure
UR urine  
Record Number:   4325 
Unique Identifier:   D004258 

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